Baimadong uranium deposit is an important alteration-type uranium deposit. On the basis of the research and analysis on major elements, trace elements and REE compositions of Qingxudong Formation black altered rock in Baimadong, weathered red clay from dolomite and Cambrian black shale, a positive correlation in concentration was found between uranium and Re, Se, Pb, Cu, As, Sb, Tl, Zn, Ni, Mo, Co, S. The content of Re, Se, Pb, Cu, As, Sb, Tl, Zn, Ni, Mo, Co, S increases with the increasing of uranium content, of which uranium and As, Co, Mo, Ni, Re, Se, Tl, Zn, S show dramatic positive correlation. Se, V, Mo concentration in soil was considered as one of the main attributes to prospect uranium deposits. According to the analysis of REE distribution pattern among Qingxudong Formation in Baimadong, Cambrian black shale and silicified dolomite of Dengying Formation, material source of Se concentration and uranium mineralization were not only originated from Niutitang Formation, but also possibly from deeper material source. Therefore, the Se concentration area is probably the area that uranium deposits are located in. The ancient slag from mercury smelting concentrates uranium, which is also worth exploring and treating.